Immune system - drug metabolism interactions: Toxicological insight
نویسندگان
چکیده
منابع مشابه
Nuclear Receptors in Drug Metabolism, Drug Response and Drug Interactions.
Orally delivered small-molecule therapeutics are metabolized in the liver and intestine by phase I and phase II drug-metabolizing enzymes (DMEs), and transport proteins coordinate drug influx (phase 0) and drug/drug-metabolite efflux (phase III). Genes involved in drug metabolism and disposition are induced by xenobiotic-activated nuclear receptors (NRs), i.e. PXR (pregnane X receptor) and CAR ...
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ژورنال
عنوان ژورنال: Adipobiology
سال: 2014
ISSN: 1313-3705,1313-3705
DOI: 10.14748/adipo.v6.1133